Article review: "Development and validation of the Arizona Cognitive Test Battery for Down syndrome" by Edgin and colleagues

My first posting about DS scientific literature is an important study published earlier this year by Jamie Edgin, Lynn Nadel, and an all-star cast of colleagues titled "Development and validation of the Arizona Cognitive Test Battery for Down syndrome."

The Arizona Cognitive Test Battery (or ACTB) is quickly becoming the center of conversation among Down syndrome researchers and clinicians interested in assessing cognitive abilities and disabilities in children, adolescents, and adults with Down syndrome.

(Click below to continue reading...)

An early start on a New Year's resolution

The calendar has almost turned to twenty-eleven and best intentions of 2010 for more regular postings here have not been very effective. So, 10 days early, here is a New Year's resolution: postings here once a week or more about basic and clinical research in Down syndrome and other neurodevelopmental disorders.

My goal is to share my thoughts and opinions about recent and significant publications relevant to DS and other forms of cognitive impairment. I'll do my best to make the findings in these studies accessible to all. If I don't, please don't hesitate to post questions and comments or email me directly.

Dan Wetmore

The blogging begins...

Hello and welcome to the new and improved Innovations in Neurodevelopmental Disorders blog -- also known as the official blog of the Stanford Down Syndrome Research Center. Follow this blog to learn about the latest research in Down syndrome at Stanford and read our thoughts on publications of interest.

To get things going, I'd like to introduce myself. My name is Dan Wetmore. My official title here at Stanford is a mouthful: I am the Neuro-innovation and Translational Neurosciences Fellow at the Stanford SINTN Institute. What this really means is that I work with Prof. Craig Garner (lab website) and the Down Syndrome Research Center to help develop and evaluate potential drug therapies for intellectual disability associated with Down syndrome and other neurodevelopmental disorders.

One reason I began working with Craig and others in the DS Research Center is due to a personal connection. My Aunt Amy has Down syndrome and is an important part of our family. Perhaps in a future post I'll write about how she (forcefully) encouraged my wife and I to get married. Here is a picture of the two of us from some years ago -- and a more recent picture of myself:



Before becoming a fellow in this group, I was an undergrad in New York City, a researcher in Cambridge, England and Boston, and a PhD student hear at Stanford. When I'm not thinking about neuroscience, I play soccer, provide free labor for my wife's garden, and root for my hometown baseball team, the St. Louis Cardinals.

I have had grand designs for many months to keep the content here new, fresh, and updated, but I must admit that other tasks here on campus have been keeping us busy. Now I'm ready for a proper 21st century contribution of blog-based idea-streaming. Let's see how I do!

Add this blog to your RSS feed (by clicking the 'Subscribe to RSS' link to the right), and if you haven't already done so 'Like' us on Facebook (link) and follow us on Twitter (link).

Please spread the word about our content here, and don't hesitate to contact me with questions, topics, or scientific publications you'd like discussed and explained.

Our relationship with the community of those interested in Down syndrome is important and works both ways. We believe that part of our mission is to communicate our findings and other relevant neuroscience insights to the DS community. And without financial philanthropic support from the DS community, our research programs would grind to a halt!

Thanks for your support. More soon...

Down syndrome clinical trial: FAQs

We frequently receive emails from parents interested in our research, clinical trial plans, and related issues. We wrote a series of FAQs to post here as a resource for parents, doctors, and educators. If you have additional questions that aren't addressed here, please contact us.

The INDD-X Team

Innovations in Neurodevelopmental Disorders at Stanford University: INDD-X

Welcome to the newly minted INDD-X website and blog!

We are a group of neuroscientists and doctors at Stanford University dedicated to understanding the causes of intellectual disability in neurodevelopmental disorders such as Down syndrome, autism, Fragile X, and more. Our labs study the basic mechanisms of brain function -- and dysfunction. But we won't stop there.

We consider it a primary goal to bring discoveries in the lab to the clinic through careful clinical trials. We strongly believe that drug therapies can reduce or resolve cognitive deficits in neurodevelopmental disorders. However, we cannot accomplish these goals alone. We have and will continue to reach out to community members, including parents, educators, doctors, and scientists to help in these efforts.

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